Difference between Binary Fission and Multiple Fission
| Binary Fission | Multiple Fission |
| Products. It gives rise to two individuals. | It forms several (more than two) individuals. |
| Conditions. Binary fission occurs under favourable conditions. | Multiple fission occurs under favourable and unfavourable conditions. |
| Nucleus. Nucleus of the parent cell divides only once to form two daughters. | Nucleus of the parent undergoes repeated divisions to form a number of daughter nuclei. |
| Cytoplasm. Cytoplasm undergoes cleavage after each nuclear division. | Cytoplasm does not divide after every nuclear division. |
| Residue. No part of the parent body is left unused. Examples. Amoeba, Paramecium. | A part of the body, covering and residual cytoplasm, is left behind. Examples. Plasmodium, Amoeba (encysted). |