Difference between Pepsin and Trypsin

Pepsin and Trypsin

Difference between pepsin and trypsin

PepsinTrypsin
Component. It is component of gastric juice.It is component of pancreatic juice.
Inactive State. It is produced in the inactive state of pepsinogen.Trypsin is produced in the inactive state called trypsinogen
Activation. The enzyme is activated by HCI of gastric juice.The enzyme is activated by enterokinase of intestinal juice.
Region of Activity. It is active in stomach.It is active in duodenum and jejunum.
Medium. It functions in acidic medium.It functions in alkaline medium.
  • In human digestive system, the enzymes pepsin and trypsin are secreted respectively by stomach and pancreas.
  • Trypsin differs from pepsin because it digests Protein, in alkaline medium in duodenum.
  • The first part of the small intestine in humans is Duodenum.
  • The enzyme that breaks down lactose is lipase.

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